US doctors manage to defeat stage four cancer - ForumDaily
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Doctors in the US managed to defeat stage four cancer

Thanks to the new procedure, American scientists managed to cure breast cancer in a woman at the last stage, this is stated in a new study published in the journal Nature, writes with the BBC.

Фото: Depositphotos

As part of the new therapy, 90 billion immune cells were introduced into the bloodstream of women.

Two years ago, doctors told Judy Perkins from Florida that she had three months to live. Today in her body there is no trace of a cancerous tumor.

A team of scientists from the National University of Cancer in the USA says that such therapy is still experimental, but over time it can become a method of treating all types of cancer.

Judy had terminal breast cancer - it was spreading quickly and was not amenable to conventional treatment.

There were tumors the size of a tennis ball in her liver, and metastases spread throughout her body.

She told reporters about her experience with experimental treatment: “About a week after starting therapy, I began to feel something. There was a tumor in my chest and I could feel it shrinking. Within another one or two weeks it completely disappeared.”

She also recalls the first CT scan after the procedure - all the medical staff “were very excited and were even jumping up and down.”

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Then she was informed that she was completely healthy.

Judy now goes camping and kayaking, and has recently traveled around her home state for five weeks.

Live therapy

The procedure is, in fact, a kind of “living medicine” that is produced from the patient’s own cells in one of the world’s leading cancer research laboratories.

“This is about the most personalized treatment imaginable,” said Dr. Steven Rosenberg, chief of surgery at the National Cancer Institute in the US.

This treatment is still experimental and requires a lot of testing and testing before it can be used widely.

But here is how it works.

It all starts with the study of the enemy.

The patient’s tumor is analyzed at the genetic level to identify rare genetic changes that can make the cancer visible to the immune system.

With 62 genetic abnormalities in the tumor of the patient, Judy Perkins, only four could become potential targets for an immune attack.

The next stage is hunting. The patient's immune system is already beginning to attack the tumor, but white blood cells are still losing out to cancer cells.

At this stage, scientists closely monitor the patient’s white blood cells and isolate those that can successfully attack the cancer. They are then grown in large quantities in laboratories.

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About 49 billion of these artificially propagated immune cells were injected into the blood of 90-year-old Judy, along with medications that “remove the brakes” on the immune system.

“The same mutations that cause cancer become its Achilles heel,” Dr. Rosenberg said.

"Paradigm Shift"

These are the results of treatment for only one patient. To confirm the findings, scientists have to conduct large-scale medical research.

The challenge so far is that immunotherapy in cancer treatment can work phenomenally for some patients - but not at all for others.

“This is a very experimental treatment and we're just learning how to do it, but it could potentially be applied to any type of cancer,” Dr. Rosenberg said. “We still have a lot of work to do, but there is potential for a complete paradigm shift in cancer treatment—creating a unique medicine for each patient—and that is a great benefit from all treatments.”

The research of American colleagues was praised by Dr. Simon Vincent of the British charity research laboratory Breast Cancer Now.

“We think these results are outstanding. This is the first opportunity to see this type of immunotherapy in the most common type of cancer. But so far it has only been tested on one patient,” notes Dr. Simon.

“There is still a lot of work to be done, but this technology could potentially open up a whole new branch of therapy for a lot of people,” he concludes.

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