In the US, developed a vaccine against cancer: it has already proven its effectiveness

Scientists from the American universities of Jefferson and Thomas Jefferson have developed, according to them, a “vaccine” against colon cancer, writes Currently,.

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The incidence of colon cancer is the third most diagnosed cancers in the world. In 2018, more than 1,8 million new cases have been reported. It is this type of cancer that is reason The death of 51 is thousands of 20 Americans every year.

Scientists said that they have created a vaccine that will “train” the immune system of a sick person to clearly and accurately direct the immune system to search for and destroy cancer cells.

On the subject: In the US, scientists have developed a vaccine to fight cancer

Ten patients with stage I and stage II colon cancer aged 40-80 took part in the clinical experiment. Each participant received one vaccination once. All ten cancer patients were surgically removed neoplasms in the colon and rectum. None of them underwent chemotherapy and radiation therapy.

For 6 months, scientists performed an immunological blood test three times.

Based on its results, it became clear to scientists that the experimental vaccine helps the human immune system “target” the GUCY2C molecule. This molecule, found in colon cancer, is a cancer cell antigen, meaning it activates “killer T cells” that kill malignant colorectal cancer cells.

All ten patients as a result of vaccination did not reveal any serious side effects and complications, and blood immunomarkers showed that the vaccine activated specific antitumor immune cells.

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“There is a need to understand what fuels the growth of colorectal cancer and use this knowledge to develop new treatments. This landmark study provides the first evidence that it is possible to safely direct a patient's own immune system to seek out and destroy this type of cancer,” said study co-author Karen E. Knudsen, MD, PhD.

“We are preparing for the second phase of the study, which will begin enrolling patients this fall,” said study co-author Adam Snook. “We used the lessons learned in the first study to modify the vaccine to hopefully make it even more effective.”

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