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Tens of thousands of dollars per course: top most expensive drugs in the US

A recent AARP report says prices for specialty drugs have more than tripled, faster than the rate of inflation. Komando.

Photo: Shutterstock

Experts have compiled a list of the 20 most expensive prescription drugs in 2022.

Depending on the medications you need, your prescriptions can cost thousands of dollars, according to AARP. Review the list below to see if any of your medications are listed. If so, get ready for tough financial times.

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Worried that you might need to buy the most expensive drug in the US? This is an understandable fear. When you hear about inflation affecting the cost of prescriptions, you might start to google "List of Expensive Drugs", "Most Expensive Prescription Drugs" or "Expensive US Prescription Drugs". Here is a list of the 20 most expensive prescription drugs:

Zokinvy
  • Manufacturer: Eiger BioPharmaceuticals.
  • Purpose: Hutchinson-Gilford progeria syndrome, which causes premature aging.
  • Monthly cost (depending on duration of therapy): $89,480.
Myalept
  • Manufacturer: Amryt Pharmaceuticals, Inc.
  • Purpose: leptin deficiency in people with generalized lipodystrophy.
  • Monthly cost (depending on duration of therapy): $77,496.
Mavenclad
  • Manufacturer: EMD Serono, Inc.
  • Purpose: multiple sclerosis.
  • Monthly cost (depending on duration of therapy): $63,993.
Raptured
  • Manufacturer: Horizon Therapeutics.
  • Purpose: disorders of the urea cycle.
  • Monthly cost (depending on duration of therapy): $57,998.
Actimmune
  • Manufacturer: Horizon Therapeutics.
  • Purpose: osteopetrosis and chronic granulomatous disease.
  • Monthly cost (depending on duration of therapy): $55,310.
Oxervate
  • Manufacturer: Dompe
  • Purpose: neurotrophic keratitis, which reduces the sensitivity of the cornea.
  • Monthly cost (depending on duration of therapy): $50,874.
Takhzyro
  • Manufacturer: Takeda.
  • Purpose: angioedema, a disease that causes swelling under the skin.
  • Monthly cost (depending on duration of therapy): $48,233.
Juxtapid
  • Manufacturer: Amryt Pharmaceuticals, Inc.
  • Purpose: homozygous familial hypercholesterolemia, which can lead to heart disease.
  • Monthly cost (depending on duration of therapy): $47,897
Gattex
  • Manufacturer: Takeda.
  • Purpose: short bowel syndrome.
  • Monthly cost (depending on duration of therapy): $42,913.
Chenodal
  • Manufacturer: Travere Therapeutics.
  • Purpose: gallstones.
  • Monthly cost (depending on duration of therapy): $42,570.
Acthar Gel
  • Manufacturer: Mallinckrodt Pharmaceuticals.
  • Purpose: lupus, rheumatoid arthritis, multiple sclerosis, infantile spasms, ophthalmic diseases and psoriatic arthritis.
  • Monthly cost (depending on duration of therapy): $41,459.
Orladeyo
  • Manufacturer: BioCryst Pharmaceuticals.
  • Purpose: hereditary angioedema.
  • Monthly cost (depending on duration of therapy): $38,427.

Tegsedi

  • Manufacturer: Akcea Therapeutics.
  • Purpose: nerve damage in hereditary transthyretin amyloidosis.
  • Monthly cost (depending on duration of therapy): $36,707.

Ayvakit

  • Manufacturer: Blueprint Medicines.
  • Purpose: gastrointestinal stromal tumors.
  • Monthly cost (depending on duration of therapy): $35,213.

Qinlock

  • Manufacturer: Deciphera Pharmaceuticals, LLC.
  • Purpose: tumors in the gastrointestinal tract.
  • Monthly cost (depending on duration of therapy): $35,199.

Korlym

  • Manufacturer: Corcept Therapeutics.
  • Purpose: high levels of cortisol in the body.
  • Monthly cost (depending on duration of therapy): $34,620.

Vitrakvi

  • Manufacturer: Bayer Pharmaceuticals.
  • Purpose: cancerous tumors with genes that fuse abnormally together.
  • Monthly cost (depending on duration of therapy): $33,784.

Recorlev

  • Manufacturer: Xeris Pharmaceuticals, Inc.
  • Purpose: endogenous Cushing's syndrome (reduces the amount of cortisol in the body).
  • Monthly cost (depending on duration of therapy): $32,400.

Cortrophin Gel

  • Manufacturer: ANI Pharmaceuticals, Inc.
  • Purpose: rheumatic diseases, collagen diseases and dermatological diseases.
  • Monthly cost (depending on duration of therapy): $31,851.

Tibsovo

  • Manufacturer: Servier Pharmaceuticals.
  • Purpose: acute myeloid leukemia, cancer of the blood and bone marrow.
  • Monthly cost (depending on duration of therapy): $30,083.

If you see any familiar names on this US drug price list, then unfortunately you need one of the most expensive prescription drugs.

Hope is not lost

You can still save on the most expensive drugs. You can talk to your doctor about trial packs, find mail-order pharmacies, or find public assistance programs. There is also a free database that you can use to search for discounts.

You may be interested in: top New York news, stories of our immigrants, and helpful tips about life in the Big Apple - read it all on ForumDaily New York.

Use Goodrxto get medicines at the best price. To find big discounts, search for your medicine in the search bar and see what prices you can find in nearby pharmacies. You don't have to register or share any personal information: it's a free tool that collects various prescription prices that you can find in pharmacies across America.

GoodRx offers big discounts on expensive prescription drugs so you can have peace of mind when you shop.

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